Sending Mixed Messages for Cell Population Control
نویسندگان
چکیده
Cells often receive signals to proliferate, but how population density is controlled is unclear. Hart et al. now show that a single secreted molecule that instructs both proliferation and death in T cells establishes a bistable response: the population is driven to either extinction or to a homeostatically defined density.
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ورودعنوان ژورنال:
- Cell
دوره 158 شماره
صفحات -
تاریخ انتشار 2014